The American College of Cardiology and the European Society of Cardiology have changed the clinical and diagnostic definition of myocardial infarction. Current technology can detect areas of myocardial necrosis under 1 g in weight. Positive blood tests for cardiac troponin or CK-MB can accurately and reliably label these small infarcts as an MI.
To diagnose acute myocardial infarction (MI): Myoglobin is a sensitive early marker often elevating within 2 hrs. Troponin I is proven specific to myocardium reaching the upper limit of normal in 4-6 hours and remaining elevated for up to 7-10 days. CK-MB reaches the upper limit of normal in 3-6 hours.
Myoglobin
CK-MB
Troponin I
2-in-1 - CK-MB/Myoglobin
2-in-1 - Troponin I/Myoglobin
3-in-1 - CK-MB/Myoglobin/Troponin I
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